What is Cartilage?


If you’ve ever wondered what cartilage is, you’re not alone. If you’re looking for information on chondrocytes, Elastic and Hyaline cartilage, or Chondroblasts, you’ve come to the right place. These are the main types of cartilage. These tissues make up about 40 to 60 percent of articular cartilage.


Chondrocytes are a type of cellular component in cartilage. They are found in cartilage in two zones. The superficial zone has a high cell density, with cells arranged in parallel clusters on the surface, and the deep zone has a sparser cell density. They are positioned in chondromas and are involved in active matrix metabolization. A pericellular domain often characterizes chondrocytes.

Elastic cartilage

Elastic cartilage is a type of tissue comprised of collagen fibers and water. It also contains proteoglycans. The most abundant proteoglycan in cartilage is Aggrecan, a glycosaminoglycans chain that has shock-absorbing and lubricating properties. In addition to collagen fiber, elastic cartilage contains noncollagenous proteins called GAGs. These proteins bind to cytokines and contribute to the organization of the extracellular matrix.

Hyaline cartilage

Hyaline cartilage is a type of connective tissue found in the joints of the human body. It forms the articular surfaces of joints, lying inside the cavity and bathed in synovial fluid. It is composed of collagen type II, but there are also small amounts of type VI collagen in hyaline cartilage.


In this study, the authors determined that progenitor cells differentiated into chondroblasts in response to intermittent mechanical stimulation. The response was correlated with changes in cellular metabolism. The transcription factors SOX9, TGFb3, and collagen type XII alpha-1 chain were upregulated. These transcription factors play essential roles in cartilage regeneration and healing.

Chondrocytes regulate epiphyseal plate growth.

This study hypothesizes that chondrocytes regulate epiphyseal growth by increasing volume, either by hypertrophy or swelling. Chondrocytes are highly responsive to osmotic changes, so a hypotonic or hypertonic challenge can cause them to swell or shrink. These changes in osmolarity allow us to identify the amount of dry and fluid cell matter in a cell.

Chondrocytes are the only cartilage cells found in hyaline cartilage

Hyaline cartilage is the most common type of cartilage found in bones and joints. It has a glassy appearance and contains collagen fibers that reinforce the structure. It is found in the ribs, larynx, nose, and throat and is the precursor of bone. It is also the weakest cartilage type because chondrocytes are the only cells found in it.

Elastic cartilage is the strongest.

Elastic cartilage is a type of cartilage with two main zones: the superficial and the middle zone. Both zones contain chondrocytes, which are round cells that have flat surfaces. They are surrounded by collagen and elastin fibers, which form a crisscrossing network. Elastic cartilage also contains perichondrium, which is the cartilage’s outer covering.

Fibrocartilage is the least flexible.

Cartilage is composed of two types: elastic and fibro. The elastic type contains more chondrocytes than fibrocartilage and is thus the most flexible. However, this type is not as flexible as hyaline cartilage. The reason for this is that the hyaline type contains fewer chondrocytes. The least flexible type is called fibrocartilage and is found in the knee and the spine vertebrae.

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